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Breast Surgeons Report Improved Visualization of Treatment Area for RT

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Based on a report presented at the illustrious San Antonio Breast Cancer Symposium 2013, the BioZorb™ three-dimensional surgical marker significantly improves visualization of the treatment area for radiation planning and therapy.

The scientific account reports that the tissue marker is easy to position, safe to use, and well tolerated by patients. During the presentation, a sequence of consecutive early-stage breast cancer patients were implanted with the device at the time of lumpectomy. The 3D BioZorb marker was reported to supply clinical advantages for surgeons and radiation oncologists.
"This device could represent a quantum leap in the ability to mark tissue for radiation treatment after surgery," said Christopher Glaser, MD, FACS, the lead author on the poster presentation. Dr. Glaser and poster co-author John Falcone, MD, are surgeons at Mitchell Memorial Cancer Center and Owensboro Health Surgical Specialists, in Owensboro, Ky.

Targeted delivery of radiation therapy helps to obstruct and prevent recurrence of cancer and is a crucial part of breast conserving therapy, the authors note. As of today, there is no standardized, accurate method for marking the surgical site of tumor excision, which makes post-operative radiation planning difficult. Methods often used for radiation planning may miscalculate the volume of the treatment area, and may lead to an excessive amount of radiation exposure to normal tissues such as the heart and lungs, resulting in inadvertent complications.bizorb

"Our radiation oncologists love this thing. Because the marker is placed directly into the surgical cavity at the time of tumor removal and sutured in place, it is very reliable. The visual difference between BioZorb targeting and traditional methods of targeting is dramatic. The marker's unique features make it easily visualized as a clear target site, helping to decrease the amount of breast and adjacent tissues exposed to radiation,” said Glaser.

The one of a kind, open-spiral design of the BioZorb marker integrates six permanent titanium clips in a set three-dimensional display and provides specific landmarks at the site of the removed tumor. This poster and other clinical presentations note that the BioZorb marker is useful for radiation treatment planning, patient positioning during treatment, and the ability to facilitate advanced methods of radiation treatment.

BioZorb has been successfully applied in both the U.S. and New Zealand. It is made of a bioabsorbable material frequently used in other medical devices, and enables the patient's body to absorb the material slowly, so it does not require surgical removal after treatments are finished.

BioZorb has been awarded 510(k) clearance from the U.S. Food and Drug Administration (FDA). The device is currently available in a variety of sizes to accommodate a range of clinical situations.

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