Nodular Duodenal Mucosa
Ectopic Gastric Mucosa
DDX

• Ectopic gastric mucosa, Burnner’s gland hyperplasia, nodular lymphoid hyperplasia, villous adenoma, varices, edema/hemorrhage, duodenitis

Solitary filling defects Duodenum

• Postinflammatory/adenomayous/hamatomatous polyp, duplication,leiomyoma/sarcoma,lipoma/sarcoma, adenocarcinoma, carcinoid choledochocele, enlarged ampulla(edema/cancer), FB, mets, ectopic pancreas

Duke DDX Duodenal Filling Defects

• Non-neoplastic masses – prolapsed antral mucosa, flexural pseudotumor, Brunner’s gland hyperplasia, lymphoid hyperplasia, normal papilla of vater, choledochocele, duplication, intramural hematoma, windsock from duodenal web, ectopic gastric mucosa

• Benign tumors
  Polyp
  GIST
  Lipoma

• Malignant Tumors
  Adenocarcinoma
  Lymphoma
  Carcinoma of the ampulla
  GIST (Leiomyosarcoma)
  Mets
  Kaposi’s