New Study Describes Imaging Findings in H7N9 Influenza

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0USA, July 1, 2013 - According to a new study found in Radiology, H7N9 pneumonia is characterized by imaging findings that differentiate it from other types of pneumonia.

Such findings include rapidly progressive changes in the lungs and pulmonary connective tissues, according to the first study to describe radiologic findings in the disease.

H7N9 is a recently discovered subtype of avian influenza virus, or bird flu.

For the study, researchers evaluated the clinical data and radiologic files of 12 patients with avian-origin influenza A H7N9 virus who were admitted to Shanghai Public Health Clinical Center between April 3, 2013, and April 20, 2013.

The intervals between the onset of symptoms and the initial imaging examinations ranged from one to six days for chest x-rays and two to nine days for computed tomography (CT).

Chest x-rays were taken every one or two days thereafter to monitor disease progression and treatment response.

The imaging findings included ground-glass opacity in all 12 patients, consolidations in 11 patients, air bronchograms in 11 patients, and interlobular septal thickening in 11 patients.

Lung lesions involved three or more lobes in all cases, but were mostly detected in right lower lobe.

Follow-up computed tomography (CT) in 10 patients showed interval improvement of the lesions in three patients and worsening of the lesions in seven patients.

Imaging findings closely mirrored the overall clinical severity of the disease.

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