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62 year old with dyspnea

Malignant Mesothelioma

  • Usually presents as plaque like thickening of the pleura > 1cm that encases whole lung
  • 80% associated with asbestos exposure
  • 20-30 year latency
  • DDX includes metaststic pleural malignancy (which is common), and indolent pleural infection
CXR shows loss of volume with extensive pleural thickening. No bony destruction
Lobulated irregular pleural thickening. Nodal enlargement

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Tumor extension into fissure with associated airspace disease

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